Impaired self-awareness in human addiction: deficient attribution of personal relevance

Highlights • Compromised self-awareness predicts severe disease and poor prognosis. • We suggest similar self-awareness impairments in human drug addiction. • This deficit is traced to ventromedial prefrontal cortex (vmPFC) functioning. • Treatment approaches to target self-awareness and vmPFC funct...

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Veröffentlicht in:	Trends in cognitive sciences 2014-12, Vol.18 (12), p.635-641
Hauptverfasser:	Moeller, Scott J, Goldstein, Rita Z
Format:	Artikel
Sprache:	eng
Schlagworte:	addiction Addictive behaviors Adult and adolescent clinical studies Awareness - physiology Biological and medical sciences Brain - physiopathology cortical midline regions Drug addiction fMRI Humans insight Medical sciences Miscellaneous Neurology personal relevance Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry RDoC criteria rostral anterior cingulate cortex Self Concept self-awareness self-processing Substance-Related Disorders - physiopathology Substance-Related Disorders - psychology Substance-Related Disorders - therapy ventromedial prefrontal cortex
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