Impaired self-awareness in human addiction: deficient attribution of personal relevance

Highlights • Compromised self-awareness predicts severe disease and poor prognosis. • We suggest similar self-awareness impairments in human drug addiction. • This deficit is traced to ventromedial prefrontal cortex (vmPFC) functioning. • Treatment approaches to target self-awareness and vmPFC funct...

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Veröffentlicht in:Trends in cognitive sciences 2014-12, Vol.18 (12), p.635-641
Hauptverfasser: Moeller, Scott J, Goldstein, Rita Z
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container_title Trends in cognitive sciences
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creator Moeller, Scott J
Goldstein, Rita Z
description Highlights • Compromised self-awareness predicts severe disease and poor prognosis. • We suggest similar self-awareness impairments in human drug addiction. • This deficit is traced to ventromedial prefrontal cortex (vmPFC) functioning. • Treatment approaches to target self-awareness and vmPFC functioning are raised.
doi_str_mv 10.1016/j.tics.2014.09.003
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source MEDLINE; Elsevier ScienceDirect Journals
subjects addiction
Addictive behaviors
Adult and adolescent clinical studies
Awareness - physiology
Biological and medical sciences
Brain - physiopathology
cortical midline regions
Drug addiction
fMRI
Humans
insight
Medical sciences
Miscellaneous
Neurology
personal relevance
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
RDoC criteria
rostral anterior cingulate cortex
Self Concept
self-awareness
self-processing
Substance-Related Disorders - physiopathology
Substance-Related Disorders - psychology
Substance-Related Disorders - therapy
ventromedial prefrontal cortex
title Impaired self-awareness in human addiction: deficient attribution of personal relevance
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