Localized delivery of doxorubicin in vivo from polymer-modified thermosensitive liposomes with MR-guided focused ultrasound-mediated heating

Thermosensitive liposomes have emerged as a viable strategy for localized delivery and triggered release of chemotherapy. MR-guided focused ultrasound (MRgFUS) has the capability of heating tumors in a controlled manner, and when combined with thermosensitive liposomes can potentially reduce tumor b...

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Veröffentlicht in:Journal of controlled release 2014-11, Vol.194, p.71-81
Hauptverfasser: Ta, Terence, Bartolak-Suki, Elizabeth, Park, Eun-Joo, Karrobi, Kavon, McDannold, Nathan J., Porter, Tyrone M.
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Sprache:eng
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