Lymphocyte transfusions prevent diabetes in the Bio-Breeding/Worcester rat

The Bio-Breeding/Worcester (BB/W) rat develops spontaneous autoimmune diabetes similar to human insulin-dependent diabetes mellitus. Transfusions of whole blood from the nondiabetic W-line of BB/W rats prevent the syndrome in diabetes-prone recipients. We report three experiments designed to determi...

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Veröffentlicht in:	The Journal of clinical investigation 1984-07, Vol.74 (1), p.39-46
Hauptverfasser:	Rossini, A A, Faustman, D, Woda, B A, Like, A A, Szymanski, I, Mordes, J P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoantibodies - analysis Blood Transfusion Concanavalin A Diabetes Mellitus, Experimental - immunology Diabetes Mellitus, Experimental - prevention & control Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - prevention & control Immunity, Innate Lymphocyte Activation Rats Rats, Inbred Strains T-Lymphocytes - transplantation
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