Penicillinase-producing plasmid types in Neisseria gonorrhoeae clinical isolates from Australia

Penicillinase-producing Neisseria gonorrhoeae (PPNG) carrying the blaTEM-135 gene is of particular concern, as it is considered a stepping stone toward resistance to extended-spectrum cephalosporins. Here, we sought to characterize plasmid types and the occurrence of the blaTEM-135 gene for N. gonor...

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Veröffentlicht in:Antimicrobial agents and chemotherapy 2014-12, Vol.58 (12), p.7576-7578
Hauptverfasser: Whiley, David, Trembizki, Ella, Buckley, Cameron, Freeman, Kevin, Lawrence, Andrew, Limnios, Athena, Pearson, Julie, Smith, Helen, Stevens, Kerrie, Lahra, Monica M
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container_end_page 7578
container_issue 12
container_start_page 7576
container_title Antimicrobial agents and chemotherapy
container_volume 58
creator Whiley, David
Trembizki, Ella
Buckley, Cameron
Freeman, Kevin
Lawrence, Andrew
Limnios, Athena
Pearson, Julie
Smith, Helen
Stevens, Kerrie
Lahra, Monica M
description Penicillinase-producing Neisseria gonorrhoeae (PPNG) carrying the blaTEM-135 gene is of particular concern, as it is considered a stepping stone toward resistance to extended-spectrum cephalosporins. Here, we sought to characterize plasmid types and the occurrence of the blaTEM-135 gene for N. gonorrhoeae clinical isolates from Australia. We found that blaTEM-135 was prevalent in Australian PPNG and was detected on all three major plasmid types.
doi_str_mv 10.1128/AAC.04120-14
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Anti-Bacterial Agents - pharmacology
Australia
Bacterial Typing Techniques
Cephalosporin Resistance
Cephalosporin Resistance - genetics
Cephalosporins - pharmacology
Gonorrhea - microbiology
Gonorrhea - transmission
Humans
Mechanisms of Resistance
Microbial Sensitivity Tests
Neisseria gonorrhoeae
Neisseria gonorrhoeae - classification
Neisseria gonorrhoeae - drug effects
Neisseria gonorrhoeae - genetics
Neisseria gonorrhoeae - isolation & purification
Penicillin Resistance
Penicillin Resistance - genetics
Penicillinase
Penicillinase - genetics
Penicillins - pharmacology
Plasmids
Plasmids - chemistry
Plasmids - classification
title Penicillinase-producing plasmid types in Neisseria gonorrhoeae clinical isolates from Australia
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