Major Role of NAD-Dependent Lactate Dehydrogenases in the Production of l-Lactic Acid with High Optical Purity by the Thermophile Bacillus coagulans

Bacillus coagulans 2-6 is an excellent producer of optically pure l-lactic acid. However, little is known about the mechanism of synthesis of the highly optically pure l-lactic acid produced by this strain. Three enzymes responsible for lactic acid production-NAD-dependent l-lactate dehydrogenase (l...

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Veröffentlicht in:	Applied and Environmental Microbiology 2014-12, Vol.80 (23), p.7134-7141
Hauptverfasser:	Wang, Limin, Cai, Yumeng, Zhu, Lingfeng, Guo, Honglian, Yu, Bo
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus - enzymology Bacillus - genetics Bacillus - metabolism Bacillus coagulans Bacteria Chemical compounds Enzymes Enzymology and Protein Engineering Fermentation Gene Expression Profiling Genes Kinetics Lactate Dehydrogenases - genetics Lactate Dehydrogenases - metabolism Lactic Acid - metabolism Lactobacillus Lactobacillus delbrueckii Lactobacillus delbrueckii - enzymology Lactobacillus delbrueckii - genetics Lactobacillus delbrueckii - metabolism Lactobacillus plantarum Lactobacillus plantarum - enzymology Lactobacillus plantarum - genetics Lactobacillus plantarum - metabolism Optics
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