Myb Permits Multilineage Airway Epithelial Cell Differentiation

The epithelium of the pulmonary airway is specially differentiated to provide defense against environmental insults, but also subject to dysregulated differentiation that results in lung disease. The current paradigm for airway epithelial differentiation is a one‐step program whereby a p63+ basal ep...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2014-12, Vol.32 (12), p.3245-3256
Hauptverfasser:	Pan, Jie-Hong, Adair-Kirk, Tracy L., Patel, Anand C., Huang, Tao, Yozamp, Nicholas S., Xu, Jian, Reddy, E. Premkumar, Byers, Derek E., Pierce, Richard A., Holtzman, Michael J., Brody, Steven L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation - physiology Cell lineage Cell Lineage - physiology Cells Cells, Cultured Chronic obstructive Cilia Cultured Cystic fibrosis Epithelial Cells - metabolism Epithelium - metabolism Humans Mice Mucous membrane Proto-Oncogene Proteins c-myb - metabolism Pulmonary disease Respiratory Mucosa - metabolism Respiratory system Respiratory System - metabolism Secretoglobins Stem Cells - cytology
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