Prognostic and Biological Significance of MicroRNA-127 Expression in Human Breast Cancer

The purpose of this study was to determine the expression of miR-127 and analyze its prognostic and biological significance in breast cancer (BC). A quantitative reverse transcription PCR assay was performed to detect the expression of miR-127 in 15 pairs of BC and corresponding noncancerous tissues...

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Veröffentlicht in:	Disease markers 2014-01, Vol.2014 (2014), p.1-12
Hauptverfasser:	Yao, Anlong, Wang, Dan, Wang, Jingjie, Li, Hanjun, Wang, Shaohua, Li, Qiurong
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - mortality Breast Neoplasms - pathology Carcinoma, Ductal, Breast - genetics Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - mortality Carcinoma, Ductal, Breast - secondary Carcinoma, Lobular - genetics Carcinoma, Lobular - metabolism Carcinoma, Lobular - mortality Carcinoma, Lobular - secondary Cell Movement Development and progression Disease-Free Survival DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Female Gene Expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects Humans Kaplan-Meier Estimate Lymphatic Metastasis MCF-7 Cells MicroRNA MicroRNAs - genetics MicroRNAs - metabolism Multivariate Analysis Prognosis Proto-Oncogene Proteins c-bcl-6 RNA Interference
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