PMP22 is critical for actin-mediated cellular functions and for establishing lipid rafts

Haploinsufficiency of peripheral myelin protein 22 (PMP22) causes hereditary neuropathy with liability to pressure palsies, a peripheral nerve lesion induced by minimal trauma or compression. As PMP22 is localized to cholesterol-enriched membrane domains that are closely linked with the underlying a...

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Veröffentlicht in:	The Journal of neuroscience 2014-11, Vol.34 (48), p.16140-16152
Hauptverfasser:	Lee, Sooyeon, Amici, Stephanie, Tavori, Hagai, Zeng, Waylon M, Freeland, Steven, Fazio, Sergio, Notterpek, Lucia
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - physiology Animals Cattle Cell Movement - physiology Cells, Cultured Female Ganglia, Spinal - physiology Male Membrane Microdomains - physiology Mice Mice, Knockout Myelin Proteins - physiology
Online-Zugang:	Volltext
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