Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment
Background Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption. Aims To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which cur...
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Veröffentlicht in: | Aging clinical and experimental research 2015-02, Vol.27 (1), p.75-82 |
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creator | Jacobson, Sandra A. Simpson, Rachel G. Lubahn, Cheri Hu, Chengcheng Belden, Christine M. Davis, Kathryn J. Nicholson, Lisa R. Long, Kathy E. Osredkar, Tracy Lorton, Dianne |
description | Background
Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption.
Aims
To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms.
Methods
A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment.
Results
Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin.
Discussion
In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated.
Conclusions
Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population. |
doi_str_mv | 10.1007/s40520-014-0238-7 |
format | Article |
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Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption.
Aims
To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms.
Methods
A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment.
Results
Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin.
Discussion
In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated.
Conclusions
Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population.</description><identifier>ISSN: 1720-8319</identifier><identifier>ISSN: 1594-0667</identifier><identifier>EISSN: 1720-8319</identifier><identifier>DOI: 10.1007/s40520-014-0238-7</identifier><identifier>PMID: 24859821</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Aged ; Aged, 80 and over ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; Cognition ; Female ; Fibromyalgia ; Fibromyalgia - drug therapy ; Fibromyalgia - physiopathology ; Fibromyalgia - psychology ; Geriatrics/Gerontology ; Humans ; Longitudinal Studies ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Older people ; Original Article ; Pain ; Pregabalin - therapeutic use ; Sleep</subject><ispartof>Aging clinical and experimental research, 2015-02, Vol.27 (1), p.75-82</ispartof><rights>Springer International Publishing Switzerland 2014</rights><rights>Aging Clinical and Experimental Research is a copyright of Springer, (2014). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c540t-feaf993abfa6daf215336e4923be1ae8e64cffe754c7a7c9a848263a2af0171f3</citedby><cites>FETCH-LOGICAL-c540t-feaf993abfa6daf215336e4923be1ae8e64cffe754c7a7c9a848263a2af0171f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40520-014-0238-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40520-014-0238-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24859821$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jacobson, Sandra A.</creatorcontrib><creatorcontrib>Simpson, Rachel G.</creatorcontrib><creatorcontrib>Lubahn, Cheri</creatorcontrib><creatorcontrib>Hu, Chengcheng</creatorcontrib><creatorcontrib>Belden, Christine M.</creatorcontrib><creatorcontrib>Davis, Kathryn J.</creatorcontrib><creatorcontrib>Nicholson, Lisa R.</creatorcontrib><creatorcontrib>Long, Kathy E.</creatorcontrib><creatorcontrib>Osredkar, Tracy</creatorcontrib><creatorcontrib>Lorton, Dianne</creatorcontrib><title>Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment</title><title>Aging clinical and experimental research</title><addtitle>Aging Clin Exp Res</addtitle><addtitle>Aging Clin Exp Res</addtitle><description>Background
Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption.
Aims
To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms.
Methods
A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment.
Results
Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin.
Discussion
In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated.
Conclusions
Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>Cognition</subject><subject>Female</subject><subject>Fibromyalgia</subject><subject>Fibromyalgia - drug therapy</subject><subject>Fibromyalgia - physiopathology</subject><subject>Fibromyalgia - psychology</subject><subject>Geriatrics/Gerontology</subject><subject>Humans</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Older people</subject><subject>Original Article</subject><subject>Pain</subject><subject>Pregabalin - therapeutic use</subject><subject>Sleep</subject><issn>1720-8319</issn><issn>1594-0667</issn><issn>1720-8319</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kctu1TAQhiMEoqXwAGyQJTZsAr4lTlggoaNykSqxgbU1yRmf4yqJg8ehCqu-Q9-QJ8HVaUtBYuXxzDf_jP0XxXPBXwvOzRvSvJK85EKXXKqmNA-KY2FyplGifXgvPiqeEJ1zrkW-PC6OpG6qtpHiuLja7CFCnzD6n5B8mFhwzPkuhnGFYeeB0TrOKYzE_MTmjOCUiFXVr8urtmIrQiQWhu1bBmwI086nZesnGBjlYGW0Dxd-2t2KsBkjeUo49cgufNozWrowJz_mjhQR0pjlnxaPHAyEz27Ok-Lbh9Ovm0_l2ZePnzfvz8q-0jyVDsG1rYLOQb0FJ0WlVI26lapDAdhgrXvn0FS6N2D6FhrdyFqBBMeFEU6dFO8OuvPSjbjt8-gIg51jXieuNoC3f1cmv7e78MNqqbU0Kgu8uhGI4fuClOzoqcdhgAnDQlbUlTacy7rJ6Mt_0POwxPxRZKXSTZvlDM-UOFB9DEQR3d0ygttry-3Bcpstt9eWW5N7Xtx_xV3HrccZkAeAcmnaYfwz-v-qvwFWqbzo</recordid><startdate>20150201</startdate><enddate>20150201</enddate><creator>Jacobson, Sandra A.</creator><creator>Simpson, Rachel G.</creator><creator>Lubahn, Cheri</creator><creator>Hu, Chengcheng</creator><creator>Belden, Christine M.</creator><creator>Davis, Kathryn J.</creator><creator>Nicholson, Lisa R.</creator><creator>Long, Kathy E.</creator><creator>Osredkar, Tracy</creator><creator>Lorton, Dianne</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150201</creationdate><title>Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment</title><author>Jacobson, Sandra A. ; Simpson, Rachel G. ; Lubahn, Cheri ; Hu, Chengcheng ; Belden, Christine M. ; Davis, Kathryn J. ; Nicholson, Lisa R. ; Long, Kathy E. ; Osredkar, Tracy ; Lorton, Dianne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c540t-feaf993abfa6daf215336e4923be1ae8e64cffe754c7a7c9a848263a2af0171f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>Cognition</topic><topic>Female</topic><topic>Fibromyalgia</topic><topic>Fibromyalgia - drug therapy</topic><topic>Fibromyalgia - physiopathology</topic><topic>Fibromyalgia - psychology</topic><topic>Geriatrics/Gerontology</topic><topic>Humans</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Older people</topic><topic>Original Article</topic><topic>Pain</topic><topic>Pregabalin - therapeutic use</topic><topic>Sleep</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jacobson, Sandra A.</creatorcontrib><creatorcontrib>Simpson, Rachel G.</creatorcontrib><creatorcontrib>Lubahn, Cheri</creatorcontrib><creatorcontrib>Hu, Chengcheng</creatorcontrib><creatorcontrib>Belden, Christine M.</creatorcontrib><creatorcontrib>Davis, Kathryn J.</creatorcontrib><creatorcontrib>Nicholson, Lisa R.</creatorcontrib><creatorcontrib>Long, Kathy E.</creatorcontrib><creatorcontrib>Osredkar, Tracy</creatorcontrib><creatorcontrib>Lorton, Dianne</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Aging clinical and experimental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jacobson, Sandra A.</au><au>Simpson, Rachel G.</au><au>Lubahn, Cheri</au><au>Hu, Chengcheng</au><au>Belden, Christine M.</au><au>Davis, Kathryn J.</au><au>Nicholson, Lisa R.</au><au>Long, Kathy E.</au><au>Osredkar, Tracy</au><au>Lorton, Dianne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment</atitle><jtitle>Aging clinical and experimental research</jtitle><stitle>Aging Clin Exp Res</stitle><addtitle>Aging Clin Exp Res</addtitle><date>2015-02-01</date><risdate>2015</risdate><volume>27</volume><issue>1</issue><spage>75</spage><epage>82</epage><pages>75-82</pages><issn>1720-8319</issn><issn>1594-0667</issn><eissn>1720-8319</eissn><abstract>Background
Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption.
Aims
To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms.
Methods
A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment.
Results
Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin.
Discussion
In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated.
Conclusions
Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>24859821</pmid><doi>10.1007/s40520-014-0238-7</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Aged, 80 and over Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Cognition Female Fibromyalgia Fibromyalgia - drug therapy Fibromyalgia - physiopathology Fibromyalgia - psychology Geriatrics/Gerontology Humans Longitudinal Studies Male Medicine Medicine & Public Health Middle Aged Older people Original Article Pain Pregabalin - therapeutic use Sleep |
title | Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment |
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