Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment

Background Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption. Aims To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which cur...

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Veröffentlicht in:Aging clinical and experimental research 2015-02, Vol.27 (1), p.75-82
Hauptverfasser: Jacobson, Sandra A., Simpson, Rachel G., Lubahn, Cheri, Hu, Chengcheng, Belden, Christine M., Davis, Kathryn J., Nicholson, Lisa R., Long, Kathy E., Osredkar, Tracy, Lorton, Dianne
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container_issue 1
container_start_page 75
container_title Aging clinical and experimental research
container_volume 27
creator Jacobson, Sandra A.
Simpson, Rachel G.
Lubahn, Cheri
Hu, Chengcheng
Belden, Christine M.
Davis, Kathryn J.
Nicholson, Lisa R.
Long, Kathy E.
Osredkar, Tracy
Lorton, Dianne
description Background Fibromyalgia (FM) has been understudied in the elderly population, a group with particular vulnerabilities to pain, reduced mobility, and sleep disruption. Aims To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms. Methods A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment. Results Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin. Discussion In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated. Conclusions Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population.
doi_str_mv 10.1007/s40520-014-0238-7
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Aims To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms. Methods A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment. Results Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin. Discussion In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated. Conclusions Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population.</description><identifier>ISSN: 1720-8319</identifier><identifier>ISSN: 1594-0667</identifier><identifier>EISSN: 1720-8319</identifier><identifier>DOI: 10.1007/s40520-014-0238-7</identifier><identifier>PMID: 24859821</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Aged ; Aged, 80 and over ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; Cognition ; Female ; Fibromyalgia ; Fibromyalgia - drug therapy ; Fibromyalgia - physiopathology ; Fibromyalgia - psychology ; Geriatrics/Gerontology ; Humans ; Longitudinal Studies ; Male ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Older people ; Original Article ; Pain ; Pregabalin - therapeutic use ; Sleep</subject><ispartof>Aging clinical and experimental research, 2015-02, Vol.27 (1), p.75-82</ispartof><rights>Springer International Publishing Switzerland 2014</rights><rights>Aging Clinical and Experimental Research is a copyright of Springer, (2014). 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Aims To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms. Methods A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment. Results Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin. Discussion In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated. 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Aims To characterize FM symptoms and treatments in a cohort of older subjects examined over time to determine the extent to which current, community-based treatment for older FM patients is in accord with published guidelines, and effective in reducing symptoms. Methods A longitudinal, observational study of 51 subjects with FM (range 55–95 years) and 81 control subjects (58–95 years) performed at Banner Sun Health Research Institute in Sun City, AZ, USA. Serial history and examination data were obtained over a 6-year period. FM data included medical history, medications, physical examination, tender point examination, neuropsychological testing, sleep and pain ratings, the Physical Function Subscale of the Fibromyalgia Impact Questionnaire, and other standardized scales to evaluate depression and other psychiatric symptoms, and cognitive and functional impairment. Results Pain and stiffness that interfered with physical activity, sleep, and mood were reported by 80 % or more of subjects. Over time, pain involved an increasing number of body areas. Over half of subjects were treated with NSAIDs, one-quarter with opioids, and one-quarter with estrogen. Few were treated with dual-acting antidepressants or pregabalin. Discussion In this cohort of elders with suboptimally treated FM, substantial persistence of symptoms was seen over time. In general, recommended treatments were either not used or not tolerated. Conclusions Age-appropriate treatments as well as education of primary care providers are needed to improve treatment of FM in the older population.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>24859821</pmid><doi>10.1007/s40520-014-0238-7</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
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1720-8319
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source MEDLINE; SpringerLink
subjects Aged
Aged, 80 and over
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Cognition
Female
Fibromyalgia
Fibromyalgia - drug therapy
Fibromyalgia - physiopathology
Fibromyalgia - psychology
Geriatrics/Gerontology
Humans
Longitudinal Studies
Male
Medicine
Medicine & Public Health
Middle Aged
Older people
Original Article
Pain
Pregabalin - therapeutic use
Sleep
title Characterization of fibromyalgia symptoms in patients 55–95 years old: a longitudinal study showing symptom persistence with suboptimal treatment
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