Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice

Metabolic diseases such as obesity and atherosclerosis result from complex interactions between environmental factors and genetic variants. A panel of chromosome substitution strains (CSSs) was developed to characterize genetic and dietary factors contributing to metabolic diseases and other biologi...

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Veröffentlicht in:	Mammalian genome 2014-12, Vol.25 (11-12), p.549-563
Hauptverfasser:	Spiezio, Sabrina H, Amon, Lynn M, McMillen, Timothy S, Vick, Cynthia M, Houston, Barbara A, Caldwell, Mark, Ogimoto, Kayoko, Morton, Gregory J, Kirk, Elizabeth A, Schwartz, Michael W, Nadeau, Joseph H, LeBoeuf, Renée C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics animal models Animals atherosclerosis Atherosclerosis - genetics Biomedical and Life Sciences Body Composition Body Weight Cell Biology chromosome substitution Chromosomes, Mammalian - genetics Diet, High-Fat - adverse effects energy expenditure Energy Metabolism - genetics environmental factors experimental diets Female females food intake Genetic Association Studies Genetic Predisposition to Disease Human Genetics Life Sciences Male males metabolic diseases mice Mice, Inbred C57BL obesity Obesity - genetics Phenotype Quantitative Trait Loci
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