Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus

The mechanism(s) and site(s) of the insulin resistance were examined in nine normal-weight noninsulin-dependent diabetic (NIDD) subjects. The euglycemic insulin clamp technique (insulin concentration approximately 100 microU/ml) was employed in combination with hepatic and femoral venous catheteriza...

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Veröffentlicht in:The Journal of clinical investigation 1985-07, Vol.76 (1), p.149-155
Hauptverfasser: DEFRONZO, R. A, GUNNARSSON, R, BJORKMAN, O, OLSSON, M, WAHREN, J
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Sprache:eng
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