Exposure of fibrinogen receptors in human platelets by surface proteolysis with elastase

Human platelets that were preincubated with porcine elastase aggregated spontaneously upon the addition of fibrinogen. Maximal aggregation to fibrinogen was observed with platelets pretreated with an elastase concentration of 111 micrograms/ml, and half-maximal aggregation occurred after treatment w...

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Veröffentlicht in:	The Journal of clinical investigation 1986-03, Vol.77 (3), p.750-756
Hauptverfasser:	KORNECKI, E, EHRLICH, Y. H, DE MARS, D. D, LENOX, R. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood Platelets - metabolism Cardiology. Vascular system Cations, Divalent - pharmacology Fibrinogen - metabolism Glycoproteins - metabolism Humans Medical sciences Membrane Proteins - metabolism Pancreatic Elastase - metabolism Platelet Aggregation - drug effects Platelet Membrane Glycoproteins Receptors, Cell Surface - metabolism
Online-Zugang:	Volltext
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