Low‐mass‐ion discriminant equation: A new concept for colorectal cancer screening

Blood metabolites can be detected as low‐mass ions (LMIs) by mass spectrometry (MS). These LMIs may reflect the pathological changes in metabolism that occur as part of a disease state, such as cancer. We constructed a LMI discriminant equation (LOME) to investigate whether systematic LMI profiling...

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Veröffentlicht in:	International journal of cancer 2014-04, Vol.134 (8), p.1844-1853
Hauptverfasser:	Lee, Jun Hwa, Kim, Kyung‐Hee, Park, Ji‐Won, Chang, Hee Jin, Kim, Byung Chang, Kim, Sun Young, Kim, Kwang Gi, Lee, Eun Sook, Kim, Dae Yong, Oh, Jae Hwan, Yoo, Byong Chul, Kim, In‐Hoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Algorithms Biological and medical sciences Biomarkers, Tumor - blood Breast cancer Breast Neoplasms - blood Breast Neoplasms - diagnosis Cancer Colorectal cancer Colorectal Neoplasms - blood Colorectal Neoplasms - diagnosis Early Detection and Diagnosis Early Detection of Cancer - methods Female Gastric cancer Gastroenterology. Liver. Pancreas. Abdomen Gene expression Humans MALDI‐TOF mass spectrometry Male Mass Screening - methods Medical research Medical sciences Medical screening Metabolites Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Occult Blood pattern recognition Principal components analysis Scientific imaging Sensitivity and Specificity serum profiling Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Stomach Neoplasms - blood Stomach Neoplasms - diagnosis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors Young Adult
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