Morphine after tubal ligation with bupivacaine: dosage versus body weight
We investigated whether there was a statistically significant difference in patient need for postoperative analgesia based on adjusted body weight between heavier and lighter women who underwent laparoscopic tubal ligation with bupivacaine injection at the skin incision. We examined 49 records of wo...
Gespeichert in:
| Veröffentlicht in: | Journal of the Society of Laparoendoscopic Surgeons 2014-10, Vol.18 (4), p.e2014.00204 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 4 |
| container_start_page | e2014.00204 |
| container_title | Journal of the Society of Laparoendoscopic Surgeons |
| container_volume | 18 |
| creator | Roehl, Bryan C Breese McCoy, Sarah J Payton, Mark E Witter, LouAnn C |
| description | We investigated whether there was a statistically significant difference in patient need for postoperative analgesia based on adjusted body weight between heavier and lighter women who underwent laparoscopic tubal ligation with bupivacaine injection at the skin incision.
We examined 49 records of women who underwent laparoscopic tubal ligation at Oklahoma State University Medical Center between 2000 and 2005 and received an injection of bupivacaine at the surgical site during the procedure. Postsurgical morphine was measured as doses per kilogram of body weight against total body weight and as total milligrams per kilogram of body weight against total body weight. A regression was performed for each measurement.
Heavier women required significantly fewer total milligrams of morphine per kilogram of body weight and fewer total doses of morphine per kilogram of body weight than lighter women (2-tailed P = .0035 and P = .0018, respectively).
Our data may suggest that lipophilic bupivacaine injected at a surgical site is held in place better and works for a longer period when more fat is present. |
| doi_str_mv | 10.4293/JSLS.2014.00204 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232407</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1627071248</sourcerecordid><originalsourceid>FETCH-LOGICAL-c393t-ff8cfb6867ea30403be1b9e0b4e0d9227f07c85cb32ba721c76addc381f165f13</originalsourceid><addsrcrecordid>eNpVkb1v2zAQxYkgRZM4nbMFHLPIPn5IpDIUKIJ8uHDRwelMkBRpM5BFh5Rs-L-v3KRBO90B7927w_0QuiIw5bRms-_LxXJKgfApAAV-gs5JzWTBRC1Oxx5kVUiQ9Rm6yPkFgJcUys_ojJZ8lICfo_mPmLbr0Dmsfe8S7gejW9yGle5D7PA-9Gtshm3YaatH1y1uYtYrh3cu5SFjE5sD3ruwWveX6JPXbXZf3usE_Xq4f757KhY_H-d33xaFZTXrC--l9aaSlXCaAQdmHDG1A8MdNDWlwoOwsrSGUaMFJVZUumksk8STqvSETdDXt9ztYDausa7rk27VNoWNTgcVdVD_K11Yq1XcKU4Z5SDGgJv3gBRfB5d7tQnZurbVnYtDVqSiAgShXI7W2ZvVpphzcv5jDQF1BKCOANQRgPoDYJy4_ve6D__fj7PfXauDEg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1627071248</pqid></control><display><type>article</type><title>Morphine after tubal ligation with bupivacaine: dosage versus body weight</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>Roehl, Bryan C ; Breese McCoy, Sarah J ; Payton, Mark E ; Witter, LouAnn C</creator><creatorcontrib>Roehl, Bryan C ; Breese McCoy, Sarah J ; Payton, Mark E ; Witter, LouAnn C</creatorcontrib><description>We investigated whether there was a statistically significant difference in patient need for postoperative analgesia based on adjusted body weight between heavier and lighter women who underwent laparoscopic tubal ligation with bupivacaine injection at the skin incision.
We examined 49 records of women who underwent laparoscopic tubal ligation at Oklahoma State University Medical Center between 2000 and 2005 and received an injection of bupivacaine at the surgical site during the procedure. Postsurgical morphine was measured as doses per kilogram of body weight against total body weight and as total milligrams per kilogram of body weight against total body weight. A regression was performed for each measurement.
Heavier women required significantly fewer total milligrams of morphine per kilogram of body weight and fewer total doses of morphine per kilogram of body weight than lighter women (2-tailed P = .0035 and P = .0018, respectively).
Our data may suggest that lipophilic bupivacaine injected at a surgical site is held in place better and works for a longer period when more fat is present.</description><identifier>ISSN: 1086-8089</identifier><identifier>EISSN: 1938-3797</identifier><identifier>DOI: 10.4293/JSLS.2014.00204</identifier><identifier>PMID: 25408604</identifier><language>eng</language><publisher>United States: Society of Laparoendoscopic Surgeons</publisher><subject>Adult ; Analgesics, Opioid - administration & dosage ; Anesthetics, Local - administration & dosage ; Body Weight ; Bupivacaine - administration & dosage ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Female ; Humans ; Laparoscopy - methods ; Ligation ; Middle Aged ; Morphine - administration & dosage ; Pain Measurement ; Pain, Postoperative - diagnosis ; Pain, Postoperative - drug therapy ; Scientific Papers ; Sterilization, Tubal - methods ; Young Adult</subject><ispartof>Journal of the Society of Laparoendoscopic Surgeons, 2014-10, Vol.18 (4), p.e2014.00204</ispartof><rights>2014 by JSLS, Journal of the Society of Laparoendoscopic Surgeons. 2014 Society of Laparoendoscopic Surgeons, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-ff8cfb6867ea30403be1b9e0b4e0d9227f07c85cb32ba721c76addc381f165f13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232407/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232407/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25408604$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Roehl, Bryan C</creatorcontrib><creatorcontrib>Breese McCoy, Sarah J</creatorcontrib><creatorcontrib>Payton, Mark E</creatorcontrib><creatorcontrib>Witter, LouAnn C</creatorcontrib><title>Morphine after tubal ligation with bupivacaine: dosage versus body weight</title><title>Journal of the Society of Laparoendoscopic Surgeons</title><addtitle>JSLS</addtitle><description>We investigated whether there was a statistically significant difference in patient need for postoperative analgesia based on adjusted body weight between heavier and lighter women who underwent laparoscopic tubal ligation with bupivacaine injection at the skin incision.
We examined 49 records of women who underwent laparoscopic tubal ligation at Oklahoma State University Medical Center between 2000 and 2005 and received an injection of bupivacaine at the surgical site during the procedure. Postsurgical morphine was measured as doses per kilogram of body weight against total body weight and as total milligrams per kilogram of body weight against total body weight. A regression was performed for each measurement.
Heavier women required significantly fewer total milligrams of morphine per kilogram of body weight and fewer total doses of morphine per kilogram of body weight than lighter women (2-tailed P = .0035 and P = .0018, respectively).
Our data may suggest that lipophilic bupivacaine injected at a surgical site is held in place better and works for a longer period when more fat is present.</description><subject>Adult</subject><subject>Analgesics, Opioid - administration & dosage</subject><subject>Anesthetics, Local - administration & dosage</subject><subject>Body Weight</subject><subject>Bupivacaine - administration & dosage</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>Humans</subject><subject>Laparoscopy - methods</subject><subject>Ligation</subject><subject>Middle Aged</subject><subject>Morphine - administration & dosage</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - diagnosis</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Scientific Papers</subject><subject>Sterilization, Tubal - methods</subject><subject>Young Adult</subject><issn>1086-8089</issn><issn>1938-3797</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkb1v2zAQxYkgRZM4nbMFHLPIPn5IpDIUKIJ8uHDRwelMkBRpM5BFh5Rs-L-v3KRBO90B7927w_0QuiIw5bRms-_LxXJKgfApAAV-gs5JzWTBRC1Oxx5kVUiQ9Rm6yPkFgJcUys_ojJZ8lICfo_mPmLbr0Dmsfe8S7gejW9yGle5D7PA-9Gtshm3YaatH1y1uYtYrh3cu5SFjE5sD3ruwWveX6JPXbXZf3usE_Xq4f757KhY_H-d33xaFZTXrC--l9aaSlXCaAQdmHDG1A8MdNDWlwoOwsrSGUaMFJVZUumksk8STqvSETdDXt9ztYDausa7rk27VNoWNTgcVdVD_K11Yq1XcKU4Z5SDGgJv3gBRfB5d7tQnZurbVnYtDVqSiAgShXI7W2ZvVpphzcv5jDQF1BKCOANQRgPoDYJy4_ve6D__fj7PfXauDEg</recordid><startdate>20141001</startdate><enddate>20141001</enddate><creator>Roehl, Bryan C</creator><creator>Breese McCoy, Sarah J</creator><creator>Payton, Mark E</creator><creator>Witter, LouAnn C</creator><general>Society of Laparoendoscopic Surgeons</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20141001</creationdate><title>Morphine after tubal ligation with bupivacaine: dosage versus body weight</title><author>Roehl, Bryan C ; Breese McCoy, Sarah J ; Payton, Mark E ; Witter, LouAnn C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-ff8cfb6867ea30403be1b9e0b4e0d9227f07c85cb32ba721c76addc381f165f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Adult</topic><topic>Analgesics, Opioid - administration & dosage</topic><topic>Anesthetics, Local - administration & dosage</topic><topic>Body Weight</topic><topic>Bupivacaine - administration & dosage</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>Humans</topic><topic>Laparoscopy - methods</topic><topic>Ligation</topic><topic>Middle Aged</topic><topic>Morphine - administration & dosage</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - diagnosis</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Scientific Papers</topic><topic>Sterilization, Tubal - methods</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roehl, Bryan C</creatorcontrib><creatorcontrib>Breese McCoy, Sarah J</creatorcontrib><creatorcontrib>Payton, Mark E</creatorcontrib><creatorcontrib>Witter, LouAnn C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the Society of Laparoendoscopic Surgeons</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roehl, Bryan C</au><au>Breese McCoy, Sarah J</au><au>Payton, Mark E</au><au>Witter, LouAnn C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Morphine after tubal ligation with bupivacaine: dosage versus body weight</atitle><jtitle>Journal of the Society of Laparoendoscopic Surgeons</jtitle><addtitle>JSLS</addtitle><date>2014-10-01</date><risdate>2014</risdate><volume>18</volume><issue>4</issue><spage>e2014.00204</spage><pages>e2014.00204-</pages><issn>1086-8089</issn><eissn>1938-3797</eissn><abstract>We investigated whether there was a statistically significant difference in patient need for postoperative analgesia based on adjusted body weight between heavier and lighter women who underwent laparoscopic tubal ligation with bupivacaine injection at the skin incision.
We examined 49 records of women who underwent laparoscopic tubal ligation at Oklahoma State University Medical Center between 2000 and 2005 and received an injection of bupivacaine at the surgical site during the procedure. Postsurgical morphine was measured as doses per kilogram of body weight against total body weight and as total milligrams per kilogram of body weight against total body weight. A regression was performed for each measurement.
Heavier women required significantly fewer total milligrams of morphine per kilogram of body weight and fewer total doses of morphine per kilogram of body weight than lighter women (2-tailed P = .0035 and P = .0018, respectively).
Our data may suggest that lipophilic bupivacaine injected at a surgical site is held in place better and works for a longer period when more fat is present.</abstract><cop>United States</cop><pub>Society of Laparoendoscopic Surgeons</pub><pmid>25408604</pmid><doi>10.4293/JSLS.2014.00204</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1086-8089 |
| ispartof | Journal of the Society of Laparoendoscopic Surgeons, 2014-10, Vol.18 (4), p.e2014.00204 |
| issn | 1086-8089 1938-3797 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232407 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult Analgesics, Opioid - administration & dosage Anesthetics, Local - administration & dosage Body Weight Bupivacaine - administration & dosage Dose-Response Relationship, Drug Drug Therapy, Combination Female Humans Laparoscopy - methods Ligation Middle Aged Morphine - administration & dosage Pain Measurement Pain, Postoperative - diagnosis Pain, Postoperative - drug therapy Scientific Papers Sterilization, Tubal - methods Young Adult |
| title | Morphine after tubal ligation with bupivacaine: dosage versus body weight |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T02%3A06%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Morphine%20after%20tubal%20ligation%20with%20bupivacaine:%20dosage%20versus%20body%20weight&rft.jtitle=Journal%20of%20the%20Society%20of%20Laparoendoscopic%20Surgeons&rft.au=Roehl,%20Bryan%20C&rft.date=2014-10-01&rft.volume=18&rft.issue=4&rft.spage=e2014.00204&rft.pages=e2014.00204-&rft.issn=1086-8089&rft.eissn=1938-3797&rft_id=info:doi/10.4293/JSLS.2014.00204&rft_dat=%3Cproquest_pubme%3E1627071248%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1627071248&rft_id=info:pmid/25408604&rfr_iscdi=true |