Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity

Intestinal alkaline phosphatase(IAP) plays an essential role in intestinal homeostasis and health through interactions with the resident microbiota, diet and the gut. IAP’s role in the intestine is to dephosphorylate toxic microbial ligands such as lipopolysaccharides, unmethylated cytosine-guanosin...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2014-11, Vol.20 (42), p.15650-15656
Hauptverfasser:	Estaki, Mehrbod, DeCoffe, Daniella, Gibson, Deanna L
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaline Alkaline Phosphatase - metabolism Alkaline Phosphatase - therapeutic use Animals Anti-Inflammatory Agents - therapeutic use Bacteria - immunology Chronic Disease Diet GPI-Linked Proteins - metabolism GPI-Linked Proteins - therapeutic use Homeostasis Host-Pathogen Interactions Humans Immunity, Mucosal Infe Inflamma-tion Inflammation - enzymology Inflammation - immunology Inflammation - microbiology Inflammatory Bowel Diseases - enzymology Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - microbiology Intestinal Intestines - drug effects Intestines - enzymology Intestines - immunology Intestines - microbiology phosphatase Signal Transduction Topic Highlight
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