New tricks for "old" domains: how novel architectures and promiscuous hubs contributed to the organization and evolution of the ECM

The extracellular matrix (ECM) is a defining characteristic of metazoans and consists of a meshwork of self-assembling, fibrous proteins, and their functionally related neighbours. Previous studies, focusing on a limited number of gene families, suggest that vertebrate complexity predominantly arose...

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Veröffentlicht in:	Genome biology and evolution 2014-10, Vol.6 (10), p.2897-2917
Hauptverfasser:	Cromar, Graham, Wong, Ka-Chun, Loughran, Noeleen, On, Tuan, Song, Hongyan, Xiong, Xuejian, Zhang, Zhaolei, Parkinson, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell adhesion & migration Evolution Evolution, Molecular Extracellular Matrix - metabolism Extracellular Matrix Proteins - metabolism Humans Proteins Tandem Repeat Sequences - genetics
Online-Zugang:	Volltext
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