Estimation of Glomerular Filtration Rate in Cynomolgus Monkeys (Macaca fascicularis)

To estimate the glomerular filtration rate (GFR) in cynomolgus monkeys (Macaca fascicularis), a three-blood-sample method using iodixanol was assessed in comparison with the conventional multisample strategy using inulin. Iodixanol and inulin were coadministered intravenously 40 mg I/kg and 50 mg/kg...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2014, Vol.76(10), pp.1423-1426
Hauptverfasser:	IWAMA, Ryosuke, SATO, Tsubasa, SAKURAI, Ken, TAKASUNA, Kiyoshi, ICHIJO, Toshihiro, FURUHAMA, Kazuhisa, SATOH, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Contrast Media - pharmacology Dose-Response Relationship, Drug glomerular filtration rate Glomerular Filtration Rate - physiology inulin Inulin - pharmacology iodixanol Laboratory Animal Science Macaca fascicularis - physiology Male monkey Reference Values serum clearance Triiodobenzoic Acids - pharmacology
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