Isolation of a Differentially Regulated Splicing Isoform of Human NF-E2

The transcription factor NF-E2 (nuclear factor erythroid 2), interacting via DNA motifs within regulatory regions of several hematopoietic genes, is thought to mediate the enhancer activity of the globin locus control regions. By screening a human fetal liver cDNA library with probes derived from mo...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1995-04, Vol.92 (8), p.3511-3515
Hauptverfasser:	Pischedda, Carla, Cocco, Sandro, Melis, Antonello, Marini, Maria Giuseppina, Kan, Yuet Wai, Cao, Antonio, Moi, Paolo
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Amino Acid Sequence Base Sequence Biochemistry cDNA Cell-Free System Cloning, Molecular Complementary DNA Deoxyribonucleic acid DNA DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Erythroid-Specific DNA-Binding Factors Exons Fetus Five prime untranslated regions Gene Expression Regulation Gene Library Genes hemoglobin Hemoglobins - biosynthesis Humans Liver man Messenger RNA Molecular Sequence Data NF-E2 protein NF-E2 Transcription Factor NF-E2 Transcription Factor, p45 Subunit nuclear factor erythroid 2 nucleotide sequence Promoter regions Promoter Regions, Genetic - genetics Protein Binding Protein Biosynthesis Protein isoforms Rodents splicing Tissue Distribution transcription factors Transcription Factors - biosynthesis Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Untranslated regions
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