Glypican 4 may be involved in the adipose tissue redistribution in high-fat feeding C57BL/6J mice with peroxisome proliferators-activated receptor γ agonist rosiglitazone treatment

Fat distribution affects the risk of developing obesity-related chronic diseases. Glypican 4 (Gpc4) may be involved in the regulation of obesity and body fat distribution. The aim of the study was to explore whether Gpc4 affects fat accumulation and the possible mechanism. C57BL/6J mice were fed wit...

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Veröffentlicht in:	Experimental and therapeutic medicine 2014-12, Vol.8 (6), p.1813-1818
Hauptverfasser:	LIU, LI, GU, HAILUN, ZHAO, YUE, AN, LI, YANG, JUN
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adipose tissues Body fat Drug therapy Food Genes glypican 4 Health aspects Heparan sulfate Hypotheses Laboratory animals Obesity peroxisome proliferators-activated receptor γ Physiological aspects Polymerase chain reaction Proteins Proteoglycans Risk factors Rodents Rosiglitazone maleate Standard deviation subcutaneous fat Variance analysis visceral fat
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