STAT3 Inhibition Induces Apoptosis in Cancer Cells Independent of STAT1 or STAT2

Signal transducers and activators of transcription (STATs) were originally discovered as mediators of signal transduction. Persistent aberrant activation of STAT3 is part of the malignant phenotype of hormone-refractory prostate cancer and pancreatic cancer; this is thought to be mediated by homodim...

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Veröffentlicht in:	Journal of molecular biochemistry 2013-02, Vol.2 (1), p.18-26
Hauptverfasser:	Shodeinde, Adetola, Ginjupalli, Kalyani, Lewis, H Dan, Riaz, Sheraz, Barton, Beverly E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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