Sevelamer Does Not Decrease Lipopolysaccharide or Soluble CD14 Levels But Decreases Soluble Tissue Factor, Low-Density Lipoprotein (LDL) Cholesterol, and Oxidized LDL Cholesterol Levels in Individuals With Untreated HIV Infection

Abnormal levels of inflammation are associated with cardiovascular disease and mortality in human immunodeficiency virus (HIV)-infected patients. Microbial translocation, which may cause inflammation, is decreased by sevelamer in patients undergoing hemodialysis. In this single-arm study, we evaluat...

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Veröffentlicht in:	The Journal of infectious diseases 2014-11, Vol.210 (10), p.1549-1554
Hauptverfasser:	Sandler, Netanya G., Zhang, Xinyan, Bosch, Ronald J., Funderburg, Nicholas T., Choi, Andrew I., Robinson, Janet K., Fine, Derek M., Coombs, Robert W., Jacobson, Jeffrey M., Landay, Alan L., Douek, Daniel C., Tressler, Randall, Read, Sarah W., Wilson, Cara C., Deeks, Steven G., Lederman, Michael M., Gandhi, Rajesh T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS Bacterial Translocation Biological and medical sciences Blood plasma Cardiovascular Agents - therapeutic use Cardiovascular Diseases - prevention & control Cholesterol, LDL - blood Cholesterols Clinical trials Fundamental and applied biological sciences. Psychology HIV HIV infections HIV Infections - complications HIV Infections - drug therapy HIV/AIDS Human immunodeficiency virus Human viral diseases Humans Infectious diseases Inflammation Lipopolysaccharide Receptors - blood Lipopolysaccharides - blood Lipoproteins, LDL - blood Major and Brief Reports Male Medical sciences Microbiology Middle Aged Polyamines - therapeutic use Registered nurses Sevelamer Solubility T lymphocytes Thromboplastin - analysis Treatment Outcome Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Young Adult
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