Microfluidic Isolation of CD34‐Positive Skin Cells Enables Regeneration of Hair and Sebaceous Glands In Vivo

This paper describes a two‐stage microfluidic system to enrich CD34‐positive (CD34+) stem cells from mouse skin with high purity. Microfluidic devices minimize the processing time of stem cells in the starting population, are easily accessible, and can be multiplexed to separate large amounts of cel...

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Veröffentlicht in:	Stem cells translational medicine 2014-11, Vol.3 (11), p.1354-1362
Hauptverfasser:	Zhu, Beili, Nahmias, Yaakov, Yarmush, Martin L., Murthy, Shashi K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allografts Animals Antigens, CD34 - metabolism CD34 antigen CD34-positive stem cells Cell Separation - methods Data analysis Defects Enabling Technologies for Cell-Based Clinical Translation Follicles Hair - cytology Hair - physiology Hydrogels Integrin alpha6 - metabolism Male Mice Mice, Inbred BALB C Mice, Nude Microfluidic Analytical Techniques - methods Microfluidic devices Microfluidics Nude mice Plastic surgery Polyethylene glycol Population Regeneration Sebaceous gland Sebaceous Glands - cytology Sebaceous Glands - physiology Skin Skin & tissue grafts Skin graft site Stem Cell Transplantation Stem cells Stem Cells - cytology Stem Cells - metabolism
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