Adolescents with clinical type 1 diabetes display reduced red blood cell glucose transporter isoform 1 (GLUT1)

Type 1 diabetic (T1D) adolescent children on insulin therapy suffer episodes of both hyper‐ and hypoglycemic episodes. Glucose transporter isoform GLUT1 expressed in blood–brain barrier (BBB) and red blood cells (RBC) compensates for perturbed circulating glucose toward protecting the supply to brai...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pediatric diabetes 2014-11, Vol.15 (7), p.511-518
Hauptverfasser:	Garg, Meena, Thamotharan, Manikkavasagar, Becker, Dorothy J, Devaskar, Sherin U
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent BBB Biomarkers - blood Blood Glucose - analysis Blood-Brain Barrier - drug effects Blood-Brain Barrier - metabolism Cognition Disorders - complications Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 1 - metabolism Down-Regulation - drug effects Enzyme-Linked Immunosorbent Assay Erythrocytes - drug effects Erythrocytes - metabolism Glucose Clamp Technique Glucose Transporter Type 1 - blood Glycated Hemoglobin A - analysis Humans Hyperglycemia - prevention & control hyperinsulinemic clamp Hypoglycemia - chemically induced Hypoglycemia - prevention & control Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use hypoglycemic clamp Insulin - pharmacology Insulin - therapeutic use Models, Biological Prospective Studies RBC glucose transporter 1 T1D
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!