Citrate synthase is a novel in vivo matrix metalloproteinase-9 substrate that regulates mitochondrial function in the postmyocardial infarction left ventricle

To evaluate the role of matrix metalloproteinase (MMP)-9 deletion on citrate synthase (CS) activity postmyocardial infarction (MI). We fractionated left ventricle (LV) samples using a differential solubility-based approach. The insoluble protein fraction was analyzed by mass spectrometry, and we ide...

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Veröffentlicht in:	Antioxidants & redox signaling 2014-11, Vol.21 (14), p.1974-1985
Hauptverfasser:	de Castro Brás, Lisandra E, Cates, Courtney A, DeLeon-Pennell, Kristine Y, Ma, Yonggang, Iyer, Rugmani Padmanabhan, Halade, Ganesh V, Yabluchanskiy, Andriy, Fields, Gregg B, Weintraub, Susan T, Lindsey, Merry L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Citrate (si)-Synthase - metabolism Forum Original Research Communications Heart Ventricles - metabolism Heart Ventricles - pathology Humans Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Mice Mice, Knockout Mitochondria - metabolism Mitochondria - pathology Myocardial Infarction - metabolism Myocardial Infarction - pathology
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