Regenerative responses after mild heart injuries for cardiomyocyte proliferation in zebrafish

Background: The zebrafish heart regenerates after various severe injuries. Common processes of heart regeneration are cardiomyocyte proliferation, activation of epicardial tissue, and neovascularization. In order to further characterize heart regeneration processes, we introduced milder injuries and...

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Veröffentlicht in:	Developmental dynamics 2014-11, Vol.243 (11), p.1477-1486
Hauptverfasser:	Itou, Junji, Akiyama, Ryutaro, Pehoski, Steve, Yu, Xiaodan, Kawakami, Hiroko, Kawakami, Yasuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cardiomyocytes Cell Proliferation - physiology Danio rerio endothelial cells Endothelial Cells - metabolism epicardial cells heart Heart Injuries - physiopathology Heart Ventricles - physiopathology Heart Ventricles - surgery Histological Techniques Image Processing, Computer-Assisted In Situ Hybridization Myocytes, Cardiac - physiology regeneration Regeneration - physiology Retinal Dehydrogenase - metabolism T-Box Domain Proteins - metabolism Wound Healing - physiology WT1 Proteins - metabolism zebrafish Zebrafish - physiology Zebrafish Proteins - metabolism
Online-Zugang:	Volltext
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