Investigation of miR-21, miR-141, and miR-221 expression levels in prostate adenocarcinoma for associated risk of recurrence after radical prostatectomy

BACKGROUND MicroRNAs (miRNAs) are small non‐coding RNAs that regulate a broad array of cellular and disease processes. Several miRNAs are differentially expressed in cancer and many are being considered as biomarkers for predicting clinical outcomes. Here we quantified the expression of three miRNAs...

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Veröffentlicht in:	The Prostate 2014-12, Vol.74 (16), p.1655-1662
Hauptverfasser:	Zheng, Qizhi, Peskoe, Sarah B., Ribas, Judit, Rafiqi, Fatema, Kudrolli, Tarana, Meeker, Alan K., De Marzo, Angelo M., Platz, Elizabeth A., Lupold, Shawn E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma - surgery Aged biochemical recurrence Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Case-Control Studies Gene Expression Regulation, Neoplastic Humans Incidence Male microRNA MicroRNAs - genetics MicroRNAs - metabolism Middle Aged miR-141 miR-21 miR-221 Multivariate Analysis Neoplasm Recurrence, Local - epidemiology Neoplasm Staging Pilot Projects Prognosis prostate cancer Prostatectomy Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Risk Factors Treatment Outcome
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