Cannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortex

Endocannabinoids acting at the cannabinoid type 1 receptor (CB1R) are known to regulate attention, cognition and mood. Previous studies have shown that, in the rat medial prefrontal cortex (mPFC), CB1R agonists increase norepinephrine release, an effect that may be attributed, in part, to CB1Rs loca...

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Veröffentlicht in:	The European journal of neuroscience 2014-10, Vol.40 (8), p.3202-3214
Hauptverfasser:	Cathel, Alessandra M., Reyes, Beverly A. S., Wang, Qin, Palma, Jonathan, Mackie, Kenneth, Van Bockstaele, Elisabeth J., Kirby, Lynn G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Adrenergic alpha-2 Receptor Agonists - pharmacology Animals Benzoxazines - pharmacology Biological and medical sciences Clonidine - pharmacology electron microscopy electrophysiology Fundamental and applied biological sciences. Psychology Gene Knock-In Techniques immunohistochemistry Male Medical sciences Mice Morpholines - pharmacology mouse Naphthalenes - pharmacology Neuropharmacology Pharmacology. Drug treatments Prefrontal Cortex - drug effects Prefrontal Cortex - physiology Prefrontal Cortex - ultrastructure Psychodysleptics: hallucinogen Psychology. Psychoanalysis. Psychiatry Psychopharmacology Pyramidal Cells - drug effects Pyramidal Cells - physiology Pyramidal Cells - ultrastructure rat Rats Rats, Sprague-Dawley Receptor, Cannabinoid, CB1 - agonists Receptor, Cannabinoid, CB1 - physiology Receptors, Adrenergic, alpha-2 - analysis Receptors, Adrenergic, alpha-2 - genetics Receptors, Adrenergic, alpha-2 - physiology Vertebrates: nervous system and sense organs
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