Focal Encephalitis Following Varicella-Zoster Virus Reactivation Without Rash in a Healthy Immunized Young Adult
Herein we describe an episode of focal varicella-zoster virus (VZV) encephalitis in a healthy young man with neither rash nor radicular pain. The symptoms began with headaches and seizures, after which magnetic resonance imaging detected a single hyperintense lesion in the left temporal lobe. Becaus...
Gespeichert in:
| Veröffentlicht in: | The Journal of infectious diseases 2014-09, Vol.210 (5), p.713-716 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 716 |
|---|---|
| container_issue | 5 |
| container_start_page | 713 |
| container_title | The Journal of infectious diseases |
| container_volume | 210 |
| creator | Halling, Geoffrey Giannini, Caterina Britton, Jeffrey W. Lee, Ricky W. Watson, Robert E. Terrell, Christine L. Parney, Ian F. Buckingham, Erin M. Carpenter, John E. Grose, Charles |
| description | Herein we describe an episode of focal varicella-zoster virus (VZV) encephalitis in a healthy young man with neither rash nor radicular pain. The symptoms began with headaches and seizures, after which magnetic resonance imaging detected a single hyperintense lesion in the left temporal lobe. Because of the provisional diagnosis of a brain tumor, the lesion was excised and submitted for pathological examination. No tumor was found. But the tissue immunostained positively for VZV antigens, and wild-type VZV sequences were detected. In short, this case represents VZV reactivation, most likely in the trigeminal ganglion, in the absence of clinical herpes zoster. |
| doi_str_mv | 10.1093/infdis/jiu137 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4202304</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>43708171</jstor_id><sourcerecordid>43708171</sourcerecordid><originalsourceid>FETCH-LOGICAL-c472t-9154a28777e0c1d6c42b186c46bc55a123dce406639b0b337770ee3aac9ffc73</originalsourceid><addsrcrecordid>eNqF0c9rFDEUB_Agil1Xjx6VXApexubXJDMXoZSuLRSEUip6CZlMppMlk6xJplL_etPOuujJ0zu8z3sk7wvAW4w-YtTSE-uH3qaTrZ0xFc_ACtdUVJxj-hysECKkwk3bHoFXKW0RQoxy8RIcEcYRawhagd0maOXguddmNypns01wE5wLP62_g7cqWm2cU9X3kLKJ8NbGOcFro3S29yrb4OFXm8cwZ3it0githwpeGOXy-AAvp2n29pfp4bcwl22n_ezya_BiUC6ZN_u6Bjeb85uzi-rqy-fLs9OrSjNBctXiminSCCEM0rjnmpEON6XwTte1woT22jDEOW071FFaIDKGKqXbYdCCrsGnZe1u7iZTrM9RObmLdlLxQQZl5b8db0d5F-4lI4jQcqc1-LBfEMOP2aQsJ5uebuFNmJPEHDe4Fqjm_6d1TSkW5eaFVgvVMaQUzXB4EUbyMU-55CmXPIt___c3DvpPgAUc74FKJcghKq_L-ME1gjGMcHHvFrdNOcRDn1GBGiww_Q3S3rY1</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1553317460</pqid></control><display><type>article</type><title>Focal Encephalitis Following Varicella-Zoster Virus Reactivation Without Rash in a Healthy Immunized Young Adult</title><source>MEDLINE</source><source>Jstor Complete Legacy</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>Alma/SFX Local Collection</source><creator>Halling, Geoffrey ; Giannini, Caterina ; Britton, Jeffrey W. ; Lee, Ricky W. ; Watson, Robert E. ; Terrell, Christine L. ; Parney, Ian F. ; Buckingham, Erin M. ; Carpenter, John E. ; Grose, Charles</creator><creatorcontrib>Halling, Geoffrey ; Giannini, Caterina ; Britton, Jeffrey W. ; Lee, Ricky W. ; Watson, Robert E. ; Terrell, Christine L. ; Parney, Ian F. ; Buckingham, Erin M. ; Carpenter, John E. ; Grose, Charles</creatorcontrib><description>Herein we describe an episode of focal varicella-zoster virus (VZV) encephalitis in a healthy young man with neither rash nor radicular pain. The symptoms began with headaches and seizures, after which magnetic resonance imaging detected a single hyperintense lesion in the left temporal lobe. Because of the provisional diagnosis of a brain tumor, the lesion was excised and submitted for pathological examination. No tumor was found. But the tissue immunostained positively for VZV antigens, and wild-type VZV sequences were detected. In short, this case represents VZV reactivation, most likely in the trigeminal ganglion, in the absence of clinical herpes zoster.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1093/infdis/jiu137</identifier><identifier>PMID: 24604820</identifier><identifier>CODEN: JIDIAQ</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Biological and medical sciences ; Brain - diagnostic imaging ; Brain - pathology ; Chickenpox ; Chickenpox vaccines ; DNA, Viral - genetics ; DNA, Viral - isolation & purification ; Encephalitis, Varicella Zoster - diagnosis ; Encephalitis, Varicella Zoster - pathology ; Encephalitis, Varicella Zoster - physiopathology ; Exanthema ; Exanthema - pathology ; Fundamental and applied biological sciences. Psychology ; Herpes zoster ; Herpesvirus 3, Human - immunology ; Herpesvirus 3, Human - isolation & purification ; Human herpesvirus 3 ; Humans ; Immunohistochemistry ; Infectious diseases ; Magnetic Resonance Imaging ; Major and Brief Reports ; Male ; Medical sciences ; Microbiology ; Miscellaneous ; Neurons ; Pain - physiopathology ; Radiography ; Seizures - diagnosis ; Seizures - etiology ; Temporal lobe ; Trigeminal ganglion ; Varicella zoster encephalitis ; Varicella-zoster virus ; Virology ; Virus Activation ; VIRUSES ; Young Adult</subject><ispartof>The Journal of infectious diseases, 2014-09, Vol.210 (5), p.713-716</ispartof><rights>Copyright © 2014 Oxford University Press on behalf of the Infectious Diseases Society of America</rights><rights>2015 INIST-CNRS</rights><rights>The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.</rights><rights>The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: . 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c472t-9154a28777e0c1d6c42b186c46bc55a123dce406639b0b337770ee3aac9ffc73</citedby><cites>FETCH-LOGICAL-c472t-9154a28777e0c1d6c42b186c46bc55a123dce406639b0b337770ee3aac9ffc73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/43708171$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/43708171$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,777,781,800,882,27905,27906,57998,58231</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28744101$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24604820$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Halling, Geoffrey</creatorcontrib><creatorcontrib>Giannini, Caterina</creatorcontrib><creatorcontrib>Britton, Jeffrey W.</creatorcontrib><creatorcontrib>Lee, Ricky W.</creatorcontrib><creatorcontrib>Watson, Robert E.</creatorcontrib><creatorcontrib>Terrell, Christine L.</creatorcontrib><creatorcontrib>Parney, Ian F.</creatorcontrib><creatorcontrib>Buckingham, Erin M.</creatorcontrib><creatorcontrib>Carpenter, John E.</creatorcontrib><creatorcontrib>Grose, Charles</creatorcontrib><title>Focal Encephalitis Following Varicella-Zoster Virus Reactivation Without Rash in a Healthy Immunized Young Adult</title><title>The Journal of infectious diseases</title><addtitle>J Infect Dis</addtitle><description>Herein we describe an episode of focal varicella-zoster virus (VZV) encephalitis in a healthy young man with neither rash nor radicular pain. The symptoms began with headaches and seizures, after which magnetic resonance imaging detected a single hyperintense lesion in the left temporal lobe. Because of the provisional diagnosis of a brain tumor, the lesion was excised and submitted for pathological examination. No tumor was found. But the tissue immunostained positively for VZV antigens, and wild-type VZV sequences were detected. In short, this case represents VZV reactivation, most likely in the trigeminal ganglion, in the absence of clinical herpes zoster.</description><subject>Biological and medical sciences</subject><subject>Brain - diagnostic imaging</subject><subject>Brain - pathology</subject><subject>Chickenpox</subject><subject>Chickenpox vaccines</subject><subject>DNA, Viral - genetics</subject><subject>DNA, Viral - isolation & purification</subject><subject>Encephalitis, Varicella Zoster - diagnosis</subject><subject>Encephalitis, Varicella Zoster - pathology</subject><subject>Encephalitis, Varicella Zoster - physiopathology</subject><subject>Exanthema</subject><subject>Exanthema - pathology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Herpes zoster</subject><subject>Herpesvirus 3, Human - immunology</subject><subject>Herpesvirus 3, Human - isolation & purification</subject><subject>Human herpesvirus 3</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Infectious diseases</subject><subject>Magnetic Resonance Imaging</subject><subject>Major and Brief Reports</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Miscellaneous</subject><subject>Neurons</subject><subject>Pain - physiopathology</subject><subject>Radiography</subject><subject>Seizures - diagnosis</subject><subject>Seizures - etiology</subject><subject>Temporal lobe</subject><subject>Trigeminal ganglion</subject><subject>Varicella zoster encephalitis</subject><subject>Varicella-zoster virus</subject><subject>Virology</subject><subject>Virus Activation</subject><subject>VIRUSES</subject><subject>Young Adult</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0c9rFDEUB_Agil1Xjx6VXApexubXJDMXoZSuLRSEUip6CZlMppMlk6xJplL_etPOuujJ0zu8z3sk7wvAW4w-YtTSE-uH3qaTrZ0xFc_ACtdUVJxj-hysECKkwk3bHoFXKW0RQoxy8RIcEcYRawhagd0maOXguddmNypns01wE5wLP62_g7cqWm2cU9X3kLKJ8NbGOcFro3S29yrb4OFXm8cwZ3it0githwpeGOXy-AAvp2n29pfp4bcwl22n_ezya_BiUC6ZN_u6Bjeb85uzi-rqy-fLs9OrSjNBctXiminSCCEM0rjnmpEON6XwTte1woT22jDEOW071FFaIDKGKqXbYdCCrsGnZe1u7iZTrM9RObmLdlLxQQZl5b8db0d5F-4lI4jQcqc1-LBfEMOP2aQsJ5uebuFNmJPEHDe4Fqjm_6d1TSkW5eaFVgvVMaQUzXB4EUbyMU-55CmXPIt___c3DvpPgAUc74FKJcghKq_L-ME1gjGMcHHvFrdNOcRDn1GBGiww_Q3S3rY1</recordid><startdate>20140901</startdate><enddate>20140901</enddate><creator>Halling, Geoffrey</creator><creator>Giannini, Caterina</creator><creator>Britton, Jeffrey W.</creator><creator>Lee, Ricky W.</creator><creator>Watson, Robert E.</creator><creator>Terrell, Christine L.</creator><creator>Parney, Ian F.</creator><creator>Buckingham, Erin M.</creator><creator>Carpenter, John E.</creator><creator>Grose, Charles</creator><general>Oxford University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7U9</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>20140901</creationdate><title>Focal Encephalitis Following Varicella-Zoster Virus Reactivation Without Rash in a Healthy Immunized Young Adult</title><author>Halling, Geoffrey ; Giannini, Caterina ; Britton, Jeffrey W. ; Lee, Ricky W. ; Watson, Robert E. ; Terrell, Christine L. ; Parney, Ian F. ; Buckingham, Erin M. ; Carpenter, John E. ; Grose, Charles</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c472t-9154a28777e0c1d6c42b186c46bc55a123dce406639b0b337770ee3aac9ffc73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Biological and medical sciences</topic><topic>Brain - diagnostic imaging</topic><topic>Brain - pathology</topic><topic>Chickenpox</topic><topic>Chickenpox vaccines</topic><topic>DNA, Viral - genetics</topic><topic>DNA, Viral - isolation & purification</topic><topic>Encephalitis, Varicella Zoster - diagnosis</topic><topic>Encephalitis, Varicella Zoster - pathology</topic><topic>Encephalitis, Varicella Zoster - physiopathology</topic><topic>Exanthema</topic><topic>Exanthema - pathology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Herpes zoster</topic><topic>Herpesvirus 3, Human - immunology</topic><topic>Herpesvirus 3, Human - isolation & purification</topic><topic>Human herpesvirus 3</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Infectious diseases</topic><topic>Magnetic Resonance Imaging</topic><topic>Major and Brief Reports</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Microbiology</topic><topic>Miscellaneous</topic><topic>Neurons</topic><topic>Pain - physiopathology</topic><topic>Radiography</topic><topic>Seizures - diagnosis</topic><topic>Seizures - etiology</topic><topic>Temporal lobe</topic><topic>Trigeminal ganglion</topic><topic>Varicella zoster encephalitis</topic><topic>Varicella-zoster virus</topic><topic>Virology</topic><topic>Virus Activation</topic><topic>VIRUSES</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Halling, Geoffrey</creatorcontrib><creatorcontrib>Giannini, Caterina</creatorcontrib><creatorcontrib>Britton, Jeffrey W.</creatorcontrib><creatorcontrib>Lee, Ricky W.</creatorcontrib><creatorcontrib>Watson, Robert E.</creatorcontrib><creatorcontrib>Terrell, Christine L.</creatorcontrib><creatorcontrib>Parney, Ian F.</creatorcontrib><creatorcontrib>Buckingham, Erin M.</creatorcontrib><creatorcontrib>Carpenter, John E.</creatorcontrib><creatorcontrib>Grose, Charles</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The Journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Halling, Geoffrey</au><au>Giannini, Caterina</au><au>Britton, Jeffrey W.</au><au>Lee, Ricky W.</au><au>Watson, Robert E.</au><au>Terrell, Christine L.</au><au>Parney, Ian F.</au><au>Buckingham, Erin M.</au><au>Carpenter, John E.</au><au>Grose, Charles</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Focal Encephalitis Following Varicella-Zoster Virus Reactivation Without Rash in a Healthy Immunized Young Adult</atitle><jtitle>The Journal of infectious diseases</jtitle><addtitle>J Infect Dis</addtitle><date>2014-09-01</date><risdate>2014</risdate><volume>210</volume><issue>5</issue><spage>713</spage><epage>716</epage><pages>713-716</pages><issn>0022-1899</issn><eissn>1537-6613</eissn><coden>JIDIAQ</coden><abstract>Herein we describe an episode of focal varicella-zoster virus (VZV) encephalitis in a healthy young man with neither rash nor radicular pain. The symptoms began with headaches and seizures, after which magnetic resonance imaging detected a single hyperintense lesion in the left temporal lobe. Because of the provisional diagnosis of a brain tumor, the lesion was excised and submitted for pathological examination. No tumor was found. But the tissue immunostained positively for VZV antigens, and wild-type VZV sequences were detected. In short, this case represents VZV reactivation, most likely in the trigeminal ganglion, in the absence of clinical herpes zoster.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>24604820</pmid><doi>10.1093/infdis/jiu137</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1899 |
| ispartof | The Journal of infectious diseases, 2014-09, Vol.210 (5), p.713-716 |
| issn | 0022-1899 1537-6613 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4202304 |
| source | MEDLINE; Jstor Complete Legacy; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection |
| subjects | Biological and medical sciences Brain - diagnostic imaging Brain - pathology Chickenpox Chickenpox vaccines DNA, Viral - genetics DNA, Viral - isolation & purification Encephalitis, Varicella Zoster - diagnosis Encephalitis, Varicella Zoster - pathology Encephalitis, Varicella Zoster - physiopathology Exanthema Exanthema - pathology Fundamental and applied biological sciences. Psychology Herpes zoster Herpesvirus 3, Human - immunology Herpesvirus 3, Human - isolation & purification Human herpesvirus 3 Humans Immunohistochemistry Infectious diseases Magnetic Resonance Imaging Major and Brief Reports Male Medical sciences Microbiology Miscellaneous Neurons Pain - physiopathology Radiography Seizures - diagnosis Seizures - etiology Temporal lobe Trigeminal ganglion Varicella zoster encephalitis Varicella-zoster virus Virology Virus Activation VIRUSES Young Adult |
| title | Focal Encephalitis Following Varicella-Zoster Virus Reactivation Without Rash in a Healthy Immunized Young Adult |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T18%3A28%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Focal%20Encephalitis%20Following%20Varicella-Zoster%20Virus%20Reactivation%20Without%20Rash%20in%20a%20Healthy%20Immunized%20Young%20Adult&rft.jtitle=The%20Journal%20of%20infectious%20diseases&rft.au=Halling,%20Geoffrey&rft.date=2014-09-01&rft.volume=210&rft.issue=5&rft.spage=713&rft.epage=716&rft.pages=713-716&rft.issn=0022-1899&rft.eissn=1537-6613&rft.coden=JIDIAQ&rft_id=info:doi/10.1093/infdis/jiu137&rft_dat=%3Cjstor_pubme%3E43708171%3C/jstor_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1553317460&rft_id=info:pmid/24604820&rft_jstor_id=43708171&rfr_iscdi=true |