Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

The innate immune receptor RIG-I is shown to sense 5′-diphosphate RNAs as found in some viral genomes in addition to its well characterized activation by RNAs bearing 5′-triphosphate moieties. Broad viral recognition by RIG-I RIG-I (retinoic acid-inducible gene I) is an important innate immune senso...

Ausführliche Beschreibung