Comparison of innate immune agonists for induction of tracheal antimicrobial peptide gene expression in tracheal epithelial cells of cattle

Bovine respiratory disease is a complex of bacterial and viral infections of economic and welfare importance to the beef industry. Although tracheal antimicrobial peptide (TAP) has microbicidal activity against bacterial pathogens causing bovine respiratory disease, risk factors for bovine respirato...

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Veröffentlicht in:	Veterinary research (Paris) 2014-10, Vol.45 (1), p.105-105, Article 105
Hauptverfasser:	Berghuis, Lesley, Abdelaziz, Khaled Taha, Bierworth, Jodi, Wyer, Leanna, Jacob, Gabriella, Karrow, Niel A, Sharif, Shayan, Clark, Mary Ellen, Caswell, Jeff L
Format:	Artikel
Sprache:	eng
Schlagworte:	agonists Animals Anti-Infective Agents - metabolism Anti-Infective Agents - pharmacology Antimicrobial Cationic Peptides - genetics antimicrobial peptides Beef industry bovine respiratory disease Cattle Cattle Diseases - immunology Comparative analysis disease resistance Disease susceptibility epithelial cells Epithelial Cells - drug effects Epithelial Cells - immunology Epithelial Cells - microbiology feedlots flagellin gene expression Gene Expression Regulation - drug effects Genetic aspects glucocorticoids Health aspects Immunity, Mucosal - drug effects innate immunity Interferon interferon-alpha Interleukins Life Sciences Ligands lipopolysaccharides Lipopolysaccharides - pharmacology Messenger RNA Mitogens oligodeoxyribonucleotides Organic acids pathogens receptors reverse transcriptase polymerase chain reaction Risk factors Toll-Like Receptors - agonists Toll-Like Receptors - genetics Toll-Like Receptors - metabolism Trachea - drug effects Trachea - immunology Trachea - microbiology
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