A phase I study of sorafenib, oxaliplatin and two days of high dose capecitabine in advanced pancreatic and biliary tract cancer: A Wisconsin Oncology Network Study

Chemotherapy has yielded minimal clinical benefit in pancreatic and biliary tract cancer. A high-dose, short course capecitabine schedule with oxaliplatin, has shown some efficacy with a lower incidence of palmar-plantar erythrodysesthesia. Achieving high exposures of the targeted agent sorafenib ma...

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Veröffentlicht in:Investigational new drugs 2012-12, Vol.31 (4), p.943-948
Hauptverfasser: LoConte, Noelle K., Holen, Kyle D., Schelman, William R., Mulkerin, Daniel L., Deming, Dustin A., Hernan, Hilary R., Traynor, Anne M., Goggins, Timothy, Groteluschen, David, Oettel, Kurt, Robinson, Emily, Lubner, Sam J.
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Sprache:eng
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