Mesenchymal-like pancreatic cancer cells harbor specific genomic alterations more frequently than their epithelial-like counterparts

The aggressiveness of pancreatic cancer is associated with the acquisition of mesenchymal characteristics by a subset of pancreatic cancer cells. The factors driving the development of this subset are not well understood. In this study, we tested the hypothesis that acquisition of a mesenchymal phen...

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Veröffentlicht in:Molecular oncology 2014-10, Vol.8 (7), p.1253-1265
Hauptverfasser: Sinha, Arkadeep, Cherba, David, Bartlam, Heather, Lenkiewicz, Elizabeth, Evers, Lisa, Barrett, Michael T., Haab, Brian B.
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Sprache:eng
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