An autonomous BMP2 regulatory element in mesenchymal cells

BMP2 is a morphogen that controls mesenchymal cell differentiation and behavior. For example, BMP2 concentration controls the differentiation of mesenchymal precursors into myocytes, adipocytes, chondrocytes, and osteoblasts. Sequences within the 3′untranslated region (UTR) of the Bmp2 mRNA mediate...

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Veröffentlicht in:	Journal of cellular biochemistry 2011-02, Vol.112 (2), p.666-674
Hauptverfasser:	Kruithof, Boudewijn P.T., Fritz, David T., Liu, Yijun, Garsetti, Diane E., Frank, David B., Pregizer, Steven K., Gaussin, Vinciane, Mortlock, Douglas P., Rogers, Melissa B.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics Animals aorta Aorta - cytology Bone Morphogenetic Protein 2 - genetics Bone Morphogenetic Protein 2 - metabolism Cell Line Cells, Cultured coronary vasculature gene regulation growth factor Immunohistochemistry Mesenchymal Stromal Cells - metabolism Mice Mice, Transgenic pathological calcification Polymerase Chain Reaction post-transcriptional Regulatory Sequences, Nucleic Acid - genetics Regulatory Sequences, Nucleic Acid - physiology
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