Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration

Embryonic heart formation requires the production of an appropriate number of cardiomyocytes; likewise, cardiac regeneration following injury relies upon the recovery of lost cardiomyocytes. The basic helix-loop-helix (bHLH) transcription factor Hand2 has been implicated in promoting cardiomyocyte f...

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Veröffentlicht in:	Development (Cambridge) 2014-08, Vol.141 (16), p.3112-3122
Hauptverfasser:	Schindler, Yocheved L, Garske, Kristina M, Wang, Jinhu, Firulli, Beth A, Firulli, Anthony B, Poss, Kenneth D, Yelon, Deborah
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Basic Helix-Loop-Helix Transcription Factors - genetics Basic Helix-Loop-Helix Transcription Factors - physiology Cell Proliferation Danio rerio DNA - chemistry Gene Expression Profiling Gene Expression Regulation, Developmental Genotype Heart - embryology In Situ Hybridization In Situ Hybridization, Fluorescence Mice Molecular Sequence Data Myocytes, Cardiac - cytology Regeneration Sequence Homology, Amino Acid Stem Cells and Regeneration Transgenes Zebrafish - embryology Zebrafish Proteins - genetics Zebrafish Proteins - physiology
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