EARLY OR LATE IL-10 BLOCKADE ENHANCES TH1 AND TH17 EFFECTOR RESPONSES AND PROMOTES FUNGAL CLEARANCE IN MICE WITH CRYPTOCOCCAL LUNG INFECTION1

The potent immunoregulatory properties of Interleukin-10 (IL-10) can counteract protective immune responses and thereby promote persistent infections as evidenced by prior studies of cryptococcal lung infection in IL-10 deficient mice. To further investigate how IL-10 impairs fungal clearance the cu...

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Veröffentlicht in:	The Journal of immunology (1950) 2014-09, Vol.193 (8), p.4107-4116
Hauptverfasser:	Murdock, Benjamin J, Teitz-Tennenbaum, Seagal, Chen, Gwo-Hsiao, Dils, Anthony J., Malachowski, Antoni N., Curtis, Jeffrey L., Olszewski, Michal A., Osterholzer, John J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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