Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling

Angiotensin (Ang) II is a potent mediator of both hypertension and cardiac damage; however, the mechanisms by which this occur remain unclear. B-cell lymphoma/leukemia 10 (Bcl10) is a member of the CBM signalosome, which links Ang II and nuclear factor-κB signaling. We hypothesized that Bcl10 is piv...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2014-11, Vol.64 (5), p.1032-1039
Hauptverfasser:	Markó, Lajos, Henke, Norbert, Park, Joon-Keun, Spallek, Bastian, Qadri, Fatimunnisa, Balogh, András, Apel, Ingrid J, Oravecz-Wilson, Katherine I, Choi, Mira, Przybyl, Lukasz, Binger, Katrina J, Haase, Nadine, Wilck, Nicola, Heuser, Arnd, Fokuhl, Verena, Ruland, Jürgen, Lucas, Peter C, McAllister-Lucas, Linda M, Luft, Friedrich C, Dechend, Ralf, Müller, Dominik N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - deficiency Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - physiology Angiotensin II - adverse effects Animals Atrial Remodeling - physiology B-Cell CLL-Lymphoma 10 Protein Cell Adhesion - physiology Cell Movement - physiology Cells, Cultured Disease Models, Animal Endothelium, Vascular - pathology Fibrosis Heart Diseases - chemically induced Heart Diseases - pathology Heart Diseases - physiopathology Mice Mice, Inbred C57BL Mice, Knockout Monocytes - pathology Myocardium - metabolism Myocardium - pathology NF-kappa B - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!