Cohort Profile: Andhra Pradesh Children and Parents Study (APCAPS)
The Andhra Pradesh Children and Parents Study (APCAPS) was originally established to study the long-term effects of early-life undernutrition on risk of cardiovascular disease. Its aims were subsequently expanded to include trans-generational influences of other environmental and genetic factors on...
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| Veröffentlicht in: | International journal of epidemiology 2014-10, Vol.43 (5), p.1417-1424 |
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| container_title | International journal of epidemiology |
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| creator | KINRA, Sanjay RADHA KRISHNA, K. V AGGARWAL, Aastha GUPTA, Ruby PRABHAKARAN, Dorairaj SRINATH REDDY, K SMITH, George Davey BEN-SHLOMO, Yoav EBRAHIM, Shah KUPER, Hannah RAMESHWAR SARMA, K. V PRABHAKARAN, Poornima GUPTA, Vipin GAGANDEEP KAUR WALIA BHOGADI, Santhi KULKARNI, Bharati KUMAR, Aniket |
| description | The Andhra Pradesh Children and Parents Study (APCAPS) was originally established to study the long-term effects of early-life undernutrition on risk of cardiovascular disease. Its aims were subsequently expanded to include trans-generational influences of other environmental and genetic factors on chronic diseases in rural India. It builds on the Hyderabad Nutrition Trial (HNT) conducted in 1987-90 to compare the effects on birthweight of a protein-calorie supplement for pregnant women and children. The index children of HNT and their mothers were retraced and examined in 2003-05, and the children re-examined as young adults aged 18-21 years in 2009-10. The cohort was expanded to include both parents and siblings of the index children in a recently completed follow-up conducted in 2010-12 (N=∼6225 out of 10,213 participants). Recruitment of the remaining residents of these 29 villages (N=∼55,000) in Ranga Reddy district of Andhra Pradesh is now under way. Extensive data on socio-demographic, lifestyle, medical, anthropometric, physiological, vascular and body composition measures, DNA, stored plasma, and assays of lipids and inflammatory markers on APCAPS participants are available. Details of how to access these data are available from the corresponding author. |
| doi_str_mv | 10.1093/ije/dyt128 |
| format | Article |
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V ; AGGARWAL, Aastha ; GUPTA, Ruby ; PRABHAKARAN, Dorairaj ; SRINATH REDDY, K ; SMITH, George Davey ; BEN-SHLOMO, Yoav ; EBRAHIM, Shah ; KUPER, Hannah ; RAMESHWAR SARMA, K. V ; PRABHAKARAN, Poornima ; GUPTA, Vipin ; GAGANDEEP KAUR WALIA ; BHOGADI, Santhi ; KULKARNI, Bharati ; KUMAR, Aniket</creator><creatorcontrib>KINRA, Sanjay ; RADHA KRISHNA, K. V ; AGGARWAL, Aastha ; GUPTA, Ruby ; PRABHAKARAN, Dorairaj ; SRINATH REDDY, K ; SMITH, George Davey ; BEN-SHLOMO, Yoav ; EBRAHIM, Shah ; KUPER, Hannah ; RAMESHWAR SARMA, K. V ; PRABHAKARAN, Poornima ; GUPTA, Vipin ; GAGANDEEP KAUR WALIA ; BHOGADI, Santhi ; KULKARNI, Bharati ; KUMAR, Aniket</creatorcontrib><description>The Andhra Pradesh Children and Parents Study (APCAPS) was originally established to study the long-term effects of early-life undernutrition on risk of cardiovascular disease. Its aims were subsequently expanded to include trans-generational influences of other environmental and genetic factors on chronic diseases in rural India. It builds on the Hyderabad Nutrition Trial (HNT) conducted in 1987-90 to compare the effects on birthweight of a protein-calorie supplement for pregnant women and children. The index children of HNT and their mothers were retraced and examined in 2003-05, and the children re-examined as young adults aged 18-21 years in 2009-10. The cohort was expanded to include both parents and siblings of the index children in a recently completed follow-up conducted in 2010-12 (N=∼6225 out of 10,213 participants). Recruitment of the remaining residents of these 29 villages (N=∼55,000) in Ranga Reddy district of Andhra Pradesh is now under way. Extensive data on socio-demographic, lifestyle, medical, anthropometric, physiological, vascular and body composition measures, DNA, stored plasma, and assays of lipids and inflammatory markers on APCAPS participants are available. Details of how to access these data are available from the corresponding author.</description><identifier>ISSN: 0300-5771</identifier><identifier>EISSN: 1464-3685</identifier><identifier>DOI: 10.1093/ije/dyt128</identifier><identifier>PMID: 24019421</identifier><identifier>CODEN: IJEPBF</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Adult ; Anthropometry ; Biological and medical sciences ; Cardiovascular Diseases - epidemiology ; Child ; Cohort Profiles ; Cohort Studies ; Cross-Sectional Studies ; Energy Intake ; Female ; General aspects ; Humans ; India ; Male ; Malnutrition - epidemiology ; Medical sciences ; Miscellaneous ; Mothers ; Nutritional Status ; Pregnancy ; Public health. 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It builds on the Hyderabad Nutrition Trial (HNT) conducted in 1987-90 to compare the effects on birthweight of a protein-calorie supplement for pregnant women and children. The index children of HNT and their mothers were retraced and examined in 2003-05, and the children re-examined as young adults aged 18-21 years in 2009-10. The cohort was expanded to include both parents and siblings of the index children in a recently completed follow-up conducted in 2010-12 (N=∼6225 out of 10,213 participants). Recruitment of the remaining residents of these 29 villages (N=∼55,000) in Ranga Reddy district of Andhra Pradesh is now under way. Extensive data on socio-demographic, lifestyle, medical, anthropometric, physiological, vascular and body composition measures, DNA, stored plasma, and assays of lipids and inflammatory markers on APCAPS participants are available. Details of how to access these data are available from the corresponding author.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>24019421</pmid><doi>10.1093/ije/dyt128</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-5771 |
| ispartof | International journal of epidemiology, 2014-10, Vol.43 (5), p.1417-1424 |
| issn | 0300-5771 1464-3685 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection; EZB Electronic Journals Library; Oxford Journals |
| subjects | Adult Anthropometry Biological and medical sciences Cardiovascular Diseases - epidemiology Child Cohort Profiles Cohort Studies Cross-Sectional Studies Energy Intake Female General aspects Humans India Male Malnutrition - epidemiology Medical sciences Miscellaneous Mothers Nutritional Status Pregnancy Public health. Hygiene Public health. Hygiene-occupational medicine Risk Factors Rural Health - statistics & numerical data Rural Population Socioeconomic Factors Time Young Adult |
| title | Cohort Profile: Andhra Pradesh Children and Parents Study (APCAPS) |
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