Short-and long-term outcome of interferon therapy for chronic hepatitis B infection

Hepatitis B virus(HBV) infection is a serious clinical problem worldwide. Conventional interferon(IFN)-α has been approved for the treatment of chronic hepatitis B(CHB). Short-term studies have demonstrated that IFN-based therapy is moderately effective in inducing the loss of hepatitis e antigen(HB...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2014-10, Vol.20 (37), p.13284-13292
Hauptverfasser:	Seo, Yasushi, Yano, Yoshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - therapeutic use Biomarkers - blood Carcinoma, Hepatocellular - prevention & control Carcinoma, Hepatocellular - virology Chronic Disease Progression DNA, Viral - blood Genotype hepatitis Hepatitis B e Antigens - blood Hepatitis B virus - drug effects Hepatitis B virus - genetics Hepatitis B virus - immunology Hepatitis B, Chronic - complications Hepatitis B, Chronic - diagnosis Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Humans Interferon Interferon-alpha - therapeutic use Liver Cirrhosis - prevention & control Liver Cirrhosis - virology Liver Neoplasms - prevention & control Liver Neoplasms - virology Risk Factors Time Factors Topic Highlight Treatment Outcome Viral Load virus Virus Replication
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