CREB-Induced Inflammation Is Important for Malignant Mesothelioma Growth

Malignant mesothelioma (MM) is an aggressive tumor with no treatment regimen. Previously we have demonstrated that cyclic AMP response element binding protein (CREB) is constitutively activated in MM tumor cells and tissues and plays an important role in MM pathogenesis. To understand the role of CR...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of pathology 2014-10, Vol.184 (10), p.2816-2827
Hauptverfasser:	Westbom, Catherine M, Shukla, Anurag, MacPherson, Maximilian B, Yasewicz, Elizabeth C, Miller, Jill M, Beuschel, Stacie L, Steele, Chad, Pass, Harvey I, Vacek, Pamela M, Shukla, Arti
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asbestos - adverse effects Cell Line, Tumor Chemokine CCL2 - metabolism Chemokines - metabolism CREB-Binding Protein - metabolism Disease Models, Animal Doxorubicin - pharmacology Gene Expression Profiling Heterografts Humans Inflammation Interleukin-6 - metabolism Interleukin-8 - metabolism Lung Neoplasms - metabolism Lung Neoplasms - pathology Male Mesothelioma - metabolism Mesothelioma - pathology Mesothelioma, Malignant Mice Mice, SCID Oligonucleotide Array Sequence Analysis Pathology Phosphorylation Regular Vascular Endothelial Growth Factor A - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!