Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses

Toxoplasma gondii is an obligate intracellular parasite that can cause severe neurological disease in infected humans. CD40 is a receptor on macrophages that plays a critical role in controlling T. gondii infection. We examined the regulation of CD40 on the surface of T. gondii-infected bone marrow-...

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Veröffentlicht in:	Infection and immunity 2014-10, Vol.82 (10), p.4047-4055
Hauptverfasser:	Morgado, Pedro, Sudarshana, Dattanand M, Gov, Lanny, Harker, Katherine S, Lam, Tonika, Casali, Paolo, Boyle, Jon P, Lodoen, Melissa B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Protozoan - immunology CD40 Antigens - biosynthesis CD40 Antigens - immunology Cells, Cultured Host Response and Inflammation Humans Interleukin-12 - immunology Macrophages - immunology Macrophages - parasitology Protozoan Proteins - immunology Toxoplasma - immunology Toxoplasma gondii
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