Management of newborn infant born to mother suffering from tuberculosis: current recommendations & gaps in knowledge

Tuberculosis (TB) is a global disease with increase in concern with growing morbidity and mortality after drug resistance and co-infection with HIV. Mother to neonatal transmission of disease is well known. Current recommendations regarding management of newborns of mothers with tuberculosis are var...

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Veröffentlicht in:Indian journal of medical research (New Delhi, India : 1994) India : 1994), 2014-07, Vol.140 (1), p.32-39
Hauptverfasser: Mittal, Hema, Das, Saurabhi, Faridi, M M A
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container_title Indian journal of medical research (New Delhi, India : 1994)
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Das, Saurabhi
Faridi, M M A
description Tuberculosis (TB) is a global disease with increase in concern with growing morbidity and mortality after drug resistance and co-infection with HIV. Mother to neonatal transmission of disease is well known. Current recommendations regarding management of newborns of mothers with tuberculosis are variable in different countries and have large gaps in the knowledge and practices. We compare and summarize here current recommendations on management of infants born to mothers with tuberculosis. Congenital tuberculosis is diagnosed by Cantwell criteria and treatment includes three or four anti-tubercular drug regimen. Prophylaxis with isoniazid (3-6 months) is recommended in neonates born to mother with TB who are infectious. Breastfeeding should be continued in these neonates and isolation is recommended only till mother is infectious, has multidrug resistant tuberculosis or non adherent to treatment. BCG vaccine is recommended at birth or after completion of prophylaxis (3-6 months) in all neonates.
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subjects Adult
Antibiotic Prophylaxis
Antitubercular Agents - therapeutic use
Babies
BCG Vaccine - therapeutic use
Congenital diseases
Demographic aspects
Disease
Disease transmission
Female
Health aspects
Humans
Immunization
Infant, Newborn
Infants (Newborn)
Infections
Infectious Disease Transmission, Vertical - prevention & control
Isoniazid - therapeutic use
Lungs
Microscopy
Mortality
Newborn babies
Pediatrics
Pregnancy
Prevention
Review
Tuberculosis
Tuberculosis - congenital
Tuberculosis - prevention & control
Tuberculosis - transmission
Viral infections
title Management of newborn infant born to mother suffering from tuberculosis: current recommendations & gaps in knowledge
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