Severe reversible myocardial injury associated with aluminium phosphide toxicity: A case report and review of literature

Aluminium phosphide is commonly used as an insecticide and can be toxic to humans at the cellular level by interfering with mitochondrial energy metabolism. We report on three cases of severe aluminium phosphide cardio-toxicity, resulting in severe decrease in both ventricular heart functions. The f...

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Veröffentlicht in:Journal Of The Saudi Heart Association 2014-10, Vol.26 (4), p.216-221
Hauptverfasser: Elabbassi, Wael, Chowdhury, Mohammed Andaleeb, Fachtartz, Arif Al Nooryani
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container_issue 4
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container_title Journal Of The Saudi Heart Association
container_volume 26
creator Elabbassi, Wael
Chowdhury, Mohammed Andaleeb
Fachtartz, Arif Al Nooryani
description Aluminium phosphide is commonly used as an insecticide and can be toxic to humans at the cellular level by interfering with mitochondrial energy metabolism. We report on three cases of severe aluminium phosphide cardio-toxicity, resulting in severe decrease in both ventricular heart functions. The first case succumbed to intractable ventricular arrhythmias complicated by multi-organ failure before she died; while the other two cases required invasive hemodynamic support and eventually improved over the course of 10–14days. We describe our experience and the challenges faced while managing one of them.
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source Elsevier ScienceDirect Journals Complete; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Aluminium phosphide toxicity
Cardiomyopathy
Case Report
Extra corporal membrane oxygenation (ECMO)
Intra-aortic balloon pump
title Severe reversible myocardial injury associated with aluminium phosphide toxicity: A case report and review of literature
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