Ligand-Controlled C(sp3)–H Arylation: Synthesis of Chiral β-Ar-β-Ar'-α-Amino Acids from Alanine

The development of ligands that can promote selective insertion of a metal into primary or secondary C(sp 3 )–H bonds is a central challenge in the field of C–H functionalization. Here, we report a rare example of catalyst-controlled primary and secondary C(sp 3 )–H arylation using two different lig...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2014-03, Vol.343 (6176), p.1216-1220
Hauptverfasser: He, Jian, Li, Suhua, Deng, Youqian, Laforteza, Brian N., Spangler, Jillian E., Yu, Jin-Quan
Format: Artikel
Sprache:eng
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