Dual modulation of type I interferon response by bluetongue virus

Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus that causes an economically important disease in ruminants. BTV infection is a strong inducer of type I interferon (IFN-I) in multiple cell types. It has been shown recently that BTV and, more specifically, the nonstructural protein NS3 o...

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Veröffentlicht in:	Journal of virology 2014-09, Vol.88 (18), p.10792-10802
Hauptverfasser:	Doceul, Virginie, Chauveau, Emilie, Lara, Estelle, Bréard, Emmanuel, Sailleau, Corinne, Zientara, Stéphan, Vitour, Damien
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bluetongue - genetics Bluetongue - metabolism Bluetongue - virology Bluetongue virus Bluetongue virus - physiology Host-Pathogen Interactions Humans Interferon Type I - genetics Interferon Type I - metabolism Janus Kinase 1 - genetics Janus Kinase 1 - metabolism Life Sciences Ruminantia Signal Transduction STAT1 Transcription Factor - genetics STAT1 Transcription Factor - metabolism Virus-Cell Interactions
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