Cell-based therapy for acute and chronic liver failures: Distinct diseases, different choices

Cell-based therapies (CBTs) are considered the effective approaches to treat liver failure. However, which cell type is the most suitable source of CBTs for acute liver failure (ALF) or chronic liver failure (CLF) remains unclear. To investigate this, mature hepatocytes in adult liver (adult HCs), f...

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Veröffentlicht in:	Scientific reports 2014-09, Vol.4 (1), p.6494, Article 6494
Hauptverfasser:	Sun, Kai, Xie, Xuqin, Xie, Jing, Jiao, Shufan, Chen, Xiaojing, Zhao, Xue, Wang, Xin, Wei, Lixin
Format:	Artikel
Sprache:	eng
Schlagworte:	13/51 14/1 38/77 38/88 64/110 64/60 692/308/1426 692/699/1503/1607 Animals Bone marrow Cell Differentiation - genetics Cell- and Tissue-Based Therapy Concanavalin A - toxicity End Stage Liver Disease - chemically induced End Stage Liver Disease - pathology End Stage Liver Disease - therapy Failure FasL protein Fetuses Gene expression Hepatocytes Hepatocytes - transplantation Humanities and Social Sciences Inflammation Interferon Interleukin 10 Liver Liver failure Liver Failure, Acute - chemically induced Liver Failure, Acute - pathology Liver Failure, Acute - therapy Liver transplantation Mesenchymal Stem Cell Transplantation Mesenchymal Stromal Cells - cytology Mesenchyme Mice multidisciplinary Regeneration Rodents Science Stem cell transplantation Stem cells Stromal cells Tumor necrosis factor
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