Induction of serpinb1a by PACAP or NGF is required for PC12 cells survival after serum withdrawal

PC12 cells are used to study the signaling mechanisms underlying the neurotrophic and neuroprotective activities of pituitary adenylate cyclase‐activating polypeptide (PACAP) and nerve growth factor (NGF). Previous microarray experiments indicated that serpinb1a was the most induced gene after 6 h o...

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Veröffentlicht in:	Journal of neurochemistry 2014-10, Vol.131 (1), p.21-32
Hauptverfasser:	Seaborn, Tommy, Ravni, Aurélia, Au, Ruby, Chow, Bill K. C., Fournier, Alain, Wurtz, Olivier, Vaudry, Hubert, Eiden, Lee E., Vaudry, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals caspase cell death Cell Survival Cell Survival - drug effects Cell Survival - physiology Cellular biology Chemical Sciences Culture Media, Serum-Free Culture Media, Serum-Free - pharmacology Kinases Life Sciences Nerve Growth Factor Nerve Growth Factor - pharmacology Neurochemistry neuroprotection PC12 Cells Pharmaceutical sciences Pharmacology Pituitary Adenylate Cyclase-Activating Polypeptide Pituitary Adenylate Cyclase-Activating Polypeptide - pharmacology Polypeptides Rats Serpins Serpins - biosynthesis Toxicology
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