Direct Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins

Despite the prevalence of the N-H aziridine motif in bioactive natural products and the clear advantages of this unprotected parent structure over N-protected derivatives as a synthetic building block, no practical methods have emerged for direct synthesis of this compound class from unfunctionalize...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 2014-01, Vol.343 (6166), p.61-65
Hauptverfasser: Jat, Jawahar L., Paudyal, Mahesh P., Gao, Hongyin, Xu, Qing-Long, Yousufuddin, Muhammed, Devarajan, Deepa, Ess, Daniel H., Kürti, László, Falck, John R.
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Sprache:eng
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