Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse

To examine the in vivo phenotype associated with hepatic metastatic lymph node 64 (MLN64) over-expression. Recombinant-adenovirus-mediated MLN64 gene transfer was used to overexpress MLN64 in the livers of C57BL/6 mice. We measured the effects of MLN64 overexpression on hepatic cholesterol content,...

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