Exercise-mediated vasodilation in human obesity and metabolic syndrome: effect of acute ascorbic acid infusion

We tested the hypothesis that infusion of ascorbic acid (AA), a potent antioxidant, would alter vasodilator responses to exercise in human obesity and metabolic syndrome (MetSyn). Forearm blood flow (FBF, Doppler ultrasound) was measured in lean, obese, and MetSyn adults (n = 39, 32 ± 2 yr). A brach...

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Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2014-09, Vol.307 (6), p.H840-H847
Hauptverfasser:	Limberg, Jacqueline K, Kellawan, J Mikhail, Harrell, John W, Johansson, Rebecca E, Eldridge, Marlowe W, Proctor, Lester T, Sebranek, Joshua J, Schrage, William G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antioxidants - administration & dosage Arterial Pressure Ascorbic Acid - administration & dosage Biomarkers - blood Blood Flow Velocity Brachial Artery - drug effects Brachial Artery - physiopathology C-Reactive Protein - metabolism Call for Papers Exercise Female Forearm - blood supply Humans Inflammation Mediators - blood Infusions, Intra-Arterial Male Metabolic Syndrome - blood Metabolic Syndrome - diagnosis Metabolic Syndrome - physiopathology Obesity - blood Obesity - diagnosis Obesity - physiopathology Regional Blood Flow Time Factors Vasodilation - drug effects Young Adult
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